Here we use Windows Interface ,Python Call in windows Interface , have access to win32com
The code is as follows ：
def DeleteQuickLaunchOnTaskBar(lnkName):
objShell = win32com.client.Dispatch("Shell.Application")
taskbarPath = os.path.join(os.environ["appdata"], r'Microsoft\Internet Explorer\Quick Launch\User Pinned\TaskBar')
lnkName = DesktopCommon.ToUnicode(lnkName)
objFolder = objShell.NameSpace(taskbarPath)
desktopItems = objFolder.Items()
for item in desktopItems:
if DesktopCommon.ToUnicode(item.Name) == lnkName:
verbs = item.Verbs()
for verb in verbs:
if DesktopCommon.ToUnicode(verb.Name) == u" Detach from the taskbar (&K)" or DesktopCommon.ToUnicode(verb.Name) == u"Unpin from Tas&kbar":
verb.DoIt() </pre> 
